A scoping review was conducted to compile existing research on the role of physical activity in multiple myeloma (MM), aiming to summarize current knowledge, map the existing literature, and pinpoint future research directions. This included a thorough search through major databases, focusing on studies that reported original data on physical activity and its correlates with MM and smoldering multiple myeloma (SMM).

The findings highlight a significant gap in the literature, particularly in longitudinal cohort studies. These studies could elucidate the associations between physical activity and MM onset, progression from SMM to MM, and the effects of specific exercise interventions based on gender and treatment types. The review also calls for the development of randomized controlled trials to assess the impacts of different exercise regimens on health outcomes for MM survivors. This underscores the need for well-designed studies to guide physical activity recommendations in this patient population.

Reference: Smith L, McCourt O, Henrich M, et al. Multiple myeloma and physical activity: a scoping review. BMJ Open. 2015 Nov 27;5(11):e009576. doi: 10.1136/bmjopen-2015-009576. Erratum in: BMJ Open. 2016;6(2):e009576corr1. PMID: 26614625; PMCID: PMC4663409.