Many patients with multiple myeloma (MM) suffer from symptoms like fatigue, diarrhea, peripheral neuropathy, and pain, despite treatment efforts. Factors such as age, comorbidities, and medication side effects increase their vulnerability. Advances in MM treatments, including monoclonal antibodies and XPO1 inhibitors, have extended survival rates but also bring side effects that impact therapy response and quality of life (QOL). Nurses are vital in managing these symptoms, providing care, and building trusted relationships with patients to encourage symptom reporting and management.

Standard MM treatments involve continuous and maintenance therapies, making effective symptom management crucial for adherence. The International Myeloma Foundation Nurse Leadership Board has published symptom management guidelines since 2008 and has updated recommendations to include newer drugs and best practices. This supplement offers practical education for patients and healthcare providers, aiming to improve patient care, manage side effects, and enhance QOL. The recommendations emphasize addressing both physical and psychosocial needs for comprehensive MM patient support.

Reference: Faiman B. Disease and Symptom Care: A Focus on Specific Needs of Patients With Multiple Myeloma. Clin J Oncol Nurs. 2017;21(5 Suppl):3-6. doi: 10.1188/17.CJON.S5.3-6.